Hennessey shocked Luther in the 2017 playoffs and the Lions were one of two Eagles victims last season.
Class 2A’s ninth-ranked team made sure it wasn’t three in a row.
Luther pulled away after a tight first quarter to hand Hennessey a 49-14 loss last Friday on the Eagles’ home field.
Peyton Wilson threw for five touchdowns and the Lions defense picked off Cole Joyce three times as Luther improved to 6-0 overall and 2-0 in District 2A-1.
Hennessey, meanwhile, fell to 0-6 and 0-3.
Joyce found Kaden Hawk for a 38-yard touchdown with 2:11 to go in the first quarter to pull the Eagles within 7-6.
It stayed that way until 7:40 left in the half when Wilson threw his second touchdown of the game, a 23-yarder to Tyler Becker. The two had previously connected from 39 yards out just 43 seconds into the contest.
Their second hook-up was the first of six straight touchdowns by Luther.
Hennessey didn’t score again until 38 seconds remained and Brysn Hunt raced into the end zone on a 25-yard run.
Hunt had a solid day as he tallied 111 yards on just nine carries. He added another 38 yards receiving on three catches and led the team with 10 tackles.
Hawk caught three passes for 46 yards and was in on five tackles.
But the Eagles couldn’t match Luther’s scoring.
Wilson’s five TDs came on just nine completions as he threw for 265 yards.
The Lions added another 248 yards on the ground, led by Cole Stastny’s 162 on 12 touches. He rushed for two TDs.
Joyce threw for 130 yards on 9 of 21 passing for the Eagles. He ran for 21 yards.
Keigen Crites added 32 rushing yards on 12 attempts.
The Eagles travel to Oklahoma Christian School in Edmond for their Week 7 contest.
Kickoff is 7 p.m. Thursday.
OCS enters the game 2-4 and 1-1 after losing 29-12 to Chisholm last week.